Spark Therapeutics was founded in 2013 and became a Member of the Roche Group in 2019. SPK-CHM and SPK-FIX are potential blockbuster products. There are 69 replacement spark plugs for Champion CJ7Y. Spark Therapeutics, a fully integrated company, strives to challenge the inevitability of genetic disease by working to discover, develop and deliver gene therapies that address inherited retinal diseases (IRDs), neurodegenerative diseases, as well as diseases that can be addressed by targeting the liver. Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. Pioneers in AAV delivery Over the past two decades, the Spark leadership team has developed unrivaled expertise in the design, manufacturing and delivery of gene therapies using adeno-associated virus (AAV) vectors. Spark's most advanced product candidate,SPK-RPE65, is in a fully-enrolled pivotal Phase 3 clinical trial for the treatment of a rare blinding condition. Acting Vice-Chair for Education, Department of Neurology. Spark's integrated gene therapy platform builds on two decades of research, development and manufacturing at The Children's Hospital of Philadelphia, including human trials conducted across diverse therapeutic areas and routes of administration. Environmental, Social and Governance (ESG), HVAC (Heating, Ventilation and Air-Conditioning), Machine Tools, Metalworking and Metallurgy, Aboriginal, First Nations & Native American, www.sparktx.com/pipeline/hematologic-disorders, http://www.prnewswire.com/news-releases/spark-therapeutics-announces-gene-therapy-collaboration-in-hemophilia-b-with-pfizer-inc-300005849.html. Spark Therapeutics (NASDAQ:ONCE), a fully integrated gene therapy company dedicated to challenging the inevitability of genetic disease, and Pfizer (NYSE:PFE), today announced that, with a cumulative follow-up of more than 18 patient years of observation (5 to 121 weeks), all 15 participants in the ongoing Phase 1/2 clinical trial of investigational SPK-9001 for severe or moderately severe . . Fully Integrated Gene Therapy Company with Deep Clinical Pipeline Spun out of The Children's Hospital of Philadelphia. Under the terms of the agreement, Spark will receive an upfront payment of $20 million and will be eligible for additional development and commercialization milestone payments of up to $260 million for multiple hemophilia B product candidates that may be developed under the collaboration. Where the organization is headquartered (e.g. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/spark-therapeutics-announces-gene-therapy-collaboration-in-hemophilia-b-with-pfizer-inc-300005849.html, Cision Distribution 888-776-0942 The open-label, randomized, controlled study builds on an earlier clinical study in which 12 patients with RPE65-related blindness demonstrated notable improvement in visual function, moving in some cases from being profoundly blind to being able to recognize faces and ambulate independently. Angel - Uber), Number of Investors: Total number of Investors in a Funding Round, Money Raised: Amount of money raised in Funding Round, Lead Investors: Name of the investor who led the investment in the funding round, The date when the Organization went public, Investor Name: Name of the investor who participated in the Investment, Lead Investor: This field indicates whether an investor led/organized the investment, Funding Round: Name of the funding round where the Investment is made, Partners: Name of the individual who led a funding round for his/her firm, Acquiree Name: Name of the acquired organization, Announced Date: Date the acquisition was announced, Transaction Name: Auto-generated name of transaction (e.g. Which types of acquisition does this organization make most frequently. Active, Closed, Last funding round type (e.g. Spark plans to leverageSPK-RPE65to address a broad spectrum of blinding conditions, and also has established a pipeline of gene therapy candidates to treat hematologic and neurodegenerative disorders. Spark Therapeutics, Inc. is a gene therapy company. Spark Therapeutics is an equal opportunity employer. Types of diversity represented in an organization, specifically of those who are founding members, currently the CEO, or have check-writing abilities in an investment firm. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Spark builds on the work of CHOP's Center for Cellular and Molecular Therapeutics (CCMT), established in 2004 as a world-class center for gene therapy translational research and manufacturing. Spark has entered into agreements with multiple academic institutions to assemble the technology, programs and capabilities needed to deliver its pioneering gene therapy products. R&D in Biotech, Environmental and various industries (no marketing product yet) Tags Biotechnology, Healthcare Venture Deals, Healthcare IPO Companies managed Acquired/Merged Spark Therapeutics Headquarters 3737 Market Street Suite 1300 Philadelphia, PA 19104 US (888) 772-7560 [email protected] Web Site N/A Milestones Related Companies Philadelphia, Pennsylvania, United States . This study provides information about the sales and revenue during the historic and forecasted period of 2021 to 2030 Iowa City, Iowa, United States. The average Spark Therapeutics salary ranges from approximately $93,180 per year for a Research Associate to $158,235 per year for a Senior Scientist.The average Spark Therapeutics hourly pay ranges from approximately $44 per hour for a Research Associate to $66 per hour for a Project Manager.Spark Therapeutics employees rate the overall compensation and benefits package 4.6/5 stars. Associate Professor of Neurology. Spark Therapeutics has acquired Genable Technologies Ltd. on Mar 7, 2016. Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. The organisation is a fully integrated, commercial company committed to discovering, developing and delivering gene therapies for genetic diseases, including inherited retinal disorders, haemophilia, lysosomal storage disorders and neurodegenerative diseases. Spark Therapeutics Inc is a United States based company operating in the field of gene therapy. "We are excited to announce our collaboration with Pfizer, as we believe it marks an important step towards bringing a potentially life-altering therapeutic to patients with hemophilia B," said Jeffrey D. Marrazzo, co-founder and chief executive officer of Spark. About. When typing in this field, a list of search results will appear and be automatically updated as you type. Media Inquiries: Jessica Rowlands 202-729-4089 [emailprotected], Cision Distribution 888-776-0942 Jul 2013 - Jul 20141 year 1 month. Get company contacts It is focused on debilitating genetic diseases by developing one-time, life-altering treatments. The company's expertise across research, clinical, regulatory and manufacturing builds on a legacy of innovation and excellence in gene therapy established by Spark's team while at The Children's Hospital of Philadelphia Center for Cellular and Molecular Therapeutics. Spark Therapeutics - Wikipedia Spark Therapeutics Spark Therapeutics, Inc. is a developer of gene therapy treatments, which treat debilitating genetic diseases. Spark Therapeutics, Inc. Feb 2020 - Dec 2020 11 months. Spark Therapeutics' relocation gives more space to the laboratory functions with approximately 22,700-square-feet of lab space, 14,800-square-feet of office/meeting/amenity space, and an additional11,200-square-feet of building support and core on the second floor and 9,000-square-feet on the garden level. About Spark Therapeutics . About Spark TherapeuticsSpark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. Their latest funding was raised on May 27, 2014 from a Series B round. Dec 08, 2014, 07:30 ET. After extensive research and analysis, Zippia's data science team found the following key financial metrics. It is a subsidiary of Hoffmann-La Roche. Sparks robust pipeline includes SPK-RPE65, a fully enrolled, pivotal Phase 3 program in blindness due to mutations in the RPE65 gene, SPK-CHM for the treatment of choroideremia, and SPK-FIX, a program for the potential treatment of hemophilia B through a global collaboration with Pfizer Inc., as well as preclinical programs to address neurodegenerative diseases and other retinal degenerative diseases and hematologic disorders. Spark Therapeutics Philadelphia, PA 19102 (PHILADELPHIA County) In-Person. Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. The founding team includes scientists who have led the advancement of gene therapy over the past two decades, establishing human proof of concept of the expression of gene. In hemophilia B, the company's Phase 1/2 study is enrolling up to 15 subjects who will receive a one-time dose through an intravenous infusion of the gene responsible for expressing factor IX. Spark Therapeutics, Inc. insights Based on 10 survey responses What people like Ability to learn new things Time and location flexibility Fair pay for job Areas for improvement Energizing work tasks Sense of belonging Overall satisfaction The best job I'll ever have Quality Control Analyst (Former Employee) - Philadelphia, PA - February 20, 2022 Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. Spark Therapeutics, Inc. PHILADELPHIA, PA, USA I February 01, 2021 I Spark Therapeutics, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY) and a fully integrated, commercial gene therapy company dedicated to challenging the inevitability of genetic . All school-age patients enrolled in the trial were able to transfer from Braille classrooms to sighted classrooms. View contacts for Spark Therapeutics to access new leads and connect with decision-makers. Which investors participated in the most funding rounds? Spark Therapeutics peak revenue was $93.5M in 2021. Genable Technologies Ltd. acquired by Spark Therapeutics, Stock ticker symbol (e.g. Spark Therapeutics Launched with $50 Million in Financing to Advance Late- and Mid-Stage Gene Therapy Programs with Clinical Proof of Concept . SPK-FIX leverages a long track record of hemophilia B gene therapy research conducted by Spark and its founding scientific team which, in prior clinical trials, has demonstrated safety and proof-of-concept in expressing Factor IX in the liver. We are working with great urgency and care to deliver gene therapy products with the potential to transform the lives of those affected by severe genetic diseases.". Spark Therapeutics to Invest $575M in New 500k Square Foot State-of-the-Art Gene Therap.. Use an on-page search by manufacturer code or . Spark Therapeutics, Inc. focuses on the development of gene therapy products for patients suffering from debilitating genetic diseases. AAPL, FB, TWTR), Total amount raised across all funding rounds, Total number of lead investment firms and individual investors, Total number of investment firms and individual investors, Announced Date: Date that the Funding Round was publicly announced, Transaction Name: Auto-generated name of transaction (e.g. Notably, Spark has exclusive rights to commercialize CHOP's proprietary manufacturing technology and will use clinical . Enrollment of approximately 20 total study participants is ongoing. Spark Therapeutics's new tradmarks suggest it is investing in R&D . The founding team includes scientists who have led the advancement of gene therapy . Name of the organization that made the acquisition, Stock ticker symbol (e.g. Director, Neurology Residency Program. This website contains information on products which is targeted to a wide range of audiences and could contain product details or information otherwise not accessible or valid in your country. The Company focuses on treating orphan diseases. What is Spark Therapeutics's Revenue? Spark Therapeutics develops gene therapies for the treatment of hemophilia and neurodegenerative diseases. Leading expertise Spark's founding team includes gene therapy scientists and experts in clinical development and manufacturing who have been at the forefront of the effort to advance gene therapy as a viable treatment paradigm for debilitating, incurable diseases. Spark Therapeutics does not accept unsolicited resumes/candidate . Read more Corporate responsibility "This agreement reinforces Pfizer's longstanding commitment to the hemophilia community. Spark Therapeutics has 368 employees, and the revenue per employee ratio is $254,076. Type Public Founded 2013 HQ Please be aware that we do not take any responsibility for accessing such information which may not comply with any legal process, regulation, registration or usage in the country of your origin. Leading gene therapy Company will partner with established market leader to develop a potential new treatment paradigm for hemophilia B. PHILADELPHIA, Dec. 8, 2014 /PRNewswire/ -- Spark Therapeutics, a late-stage gene therapy company developing treatments for debilitating genetic diseases, announced today that it has entered into a global collaboration with Pfizer Inc. for the development and potential commercialization of SPK-FIX, a development program advancing proprietary, bio-engineered adeno-associated virus (AAV) vectors for the potential treatment of hemophilia B. They acquired Genable Technologies Ltd. for $15.2M. Its products include vor etigene neparvovec, which is in Phase III clinical trial for the treatment of genetic blinding conditions called inherited retinal diseases caused by non sex-linked, autosomal recessive . We are a force of over 90,000 people working together across more than 100 countries. Spark Therapeutics will receive the option to exclusively license a defined number of synthetic promoters emerging from the collaboration for use in developing gene therapy products in specified . The Gene Therapy Medicinal Products (GTMP) Market research report includes Market segmentation and overlays shadow upon the leading market players highlighting the favourable competitive landscape and trends prevailing over the years. About Spark Therapeutics Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. To learn more, visitwww.sparktx.com. "The collaboration also marks another milestone for Spark, following our recent clinical and regulatory progress and key leadership hires.". Contact Email [email protected]. Spark Therapeutics is focused on the development of treatments for genetic diseases. AAPL, FB, TWTR), Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Descriptive keyword for an Organization (e.g. PHILADELPHIA, Nov. 6, 2014 /PRNewswire/ -- Spark Therapeutics, a late-stage gene therapy company developing treatments for debilitating genetic diseases, announced today that its lead product . Spark Therapeutics is developing curative, one-time gene therapy products with the potential to transform the lives of patients and re-imagine the treatment of . "Filtering down to just Philadelphia proper does reveal that . Detailed information on company financials and operating reports can be found here: . and menstrual hygiene products to women experiencing homelessness . from 8 AM - 9 PM ET. Spark Therapeutics has an overall rating of 4.4 out of 5, based on over 72 reviews left anonymously by employees. Its products include LUXTURNA (voretigene neparvovec) for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy and viable retinal cells. Part # 7034. "Their vision and long-term dedication have enabled us to effectively address many of the key challenges facing the field and to emerge with one of the industry's most robust clinical-stage gene therapy pipelines; as well as exclusive rights to commercialize a proprietary manufacturing platform, supply from a world-class manufacturing facility and a founding team with a proven track record of executing safe and effective gene therapy trials for nearly two decades. High, M.D, a gene therapy pioneer who has served as the director of the CCMT since its inception. Our robust pipeline includes a Phase 3 program in blindness due to mutations in the RPE65 gene and a Phase 1/2 program in hemophilia B, as well as preclinical programs to address neurodegenerative diseases and other retinal degenerative diseases and hematologic disorders. from 8 AM - 9 PM ET. Contents 1 History 2 Products and pipeline 2.1 Voretigene neparvovec 2.2 Fidanacogene elaparvovec 2.3 SPK-8011 2.4 SPK-7001 2.5 SPK-3006 Navigate a database of ~2k spark plugs and cross - reference products for them. Current treatment requires recurrent intravenous infusions of either plasma-derived or recombinant Factor IX to control bleeding episodes. If successful, gene therapy in hemophilia B would eliminate or reduce the need for regular infusions of clotting factor, enabling physicians to provide comprehensive, accessible treatment to all hemophilia B patients, potentially including those with inhibiting antibodies. SaaS, Android, Cloud Computing, Medical Device). Seed, Series A, Private Equity), Whether an Organization is for profit or non-profit, General contact email for the organization, Auto-generated name of transaction (e.g. Spark Therapeutics, Inc. 3737 Market Street Philadelphia, PA 19104 Phone: 1-855-SPARKTX / +1 215-220-9300 2022 Spark Therapeutics, Inc. P-RPE65-US-450002-10
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